Instem, Booth 306
Provantis®
As the #1 preclinical software suite for organizations engaged in non-clinical evaluation studies, Provantis streamlines processes and workflows with straightforward, intuitive functionality for simple and complex studies within both GLP and non-GLP environments.
Learn more about the significant updates to our Pathology suite, including enhanced capabilities for digital pathology as well as Spotlighter™, our historical data solution that helps you find the hidden value in your reference data.
SEND Solutions
The most comprehensive and widely deployed set of software (submit™) and services (SEND Advantage™) supporting the creation and management of SEND datasets. Stop by our booth to learn more about our two latest software solutions, DefineNow™ for the creation and editing of define.xml files and GuidePro™, Instem’s Study Data Reviewer’s Guide generator.
Genetic Toxicology
Image analysis and data management solutions helping users better collect, manage, review and extract data while transitioning information into insight, utilizing our Comet Assay IV and Cyto Study Manager tools. Also, don’t miss the opportunity to learn more about our new Transgenic Rodent Assay module!
Advance™ Weight of Evidence Assessments
Instem’s latest In Silico service which is re-imagining the way organizations perform carcinogenicity assessments via the 6 Weight of Evidence (WoE) factors under the ICH S1B guideline.
KnowledgeScan™ Target Safety Assessment (TSA) Service
Delivering comprehensive TSAs for clients around the world, enabling them to make faster, better-informed decisions on their drug targets.
Watch the KnowledgeScan Explainer video
Leadscope Model Applier™
Advanced informatics and prediction technology, together with comprehensive database solutions that are helping organizations effectively unlock valuable knowledge contained in both public and proprietary sources of research data.
Predict™ In Silico Toxicology service
A leading edge, technology-enabled service that delivers a combination of powerful computation models with expert scientific review, to help clients predict chemical safety more quickly, efficiently and comprehensively.
Centrus®
An innovative technology platform that delivers a combination of pioneering, well-integrated computing modules, along with a comprehensive catalogue of non-clinical and clinical data.
If you would like to schedule a discussion with us during ACT contact us at [email protected] indicating your area of interest.
Instem Event Schedule
Tuesday, November 19
Symposium Presentation: In Silico Methods for the Derivation of Quantitative Safety Limits
Session Title: Managing Nonmutagenic Impurities in Pharmaceuticals: Emerging Science (S13)
Speaker: Arianna Bassan, PhD, Principal Consultant, Innovatune
Session Date and Time: Tuesday, November 19, 2024 – 4.15-4.35pm
Wednesday, November 20
Exhibitor Hosted Event: Information into Insights: How to reuse your SEND data within an S1B submission
This presentation will examine the recent ICH S1B (R1) WoE Addendum – which explains how the two-year rat carcinogenicity test can be removed from the testing program if there is sufficient data already available to discredit (or prove) a cancer risk. If a two-year rat carcinogenicity test will not add value, then it can be negated in lieu of a comprehensive WoE dossier. Using a SEND package, which is already structured, standardized and machine readable, we show how the data can be interrogated to provide evidence for specific factors (e.g. histopathology and genetic toxicology) from the S1B guideline.
Attendees of this presentation will gain insights into the growing prominence of WoE approaches in safety assessments, learning specifically how SEND datasets can facilitate the incorporation of relevant preclinical data into specific factors. Ultimately, we will provide a deeper understanding of how leveraging existing data can streamline safety assessments and potentially revolutionize regulatory practices.
Presenters: Frances Hall, PhD, Scientific Application Director, In Silico and Translational Science Solutions, Instem and Marc Ellison, Director, SEND Solutions, Instem
Session Date & Time: Wednesday November 20, 12:00-12.55 PM
Room Location: 203
We are also pleased to be involved in the following posters:
Poster Number: P423
Abstract Title: Development of fit-for-purpose in silico models for the assessment of extractables and leachables
Presenting Author: Kevin Cross, PhD, VP Regulatory Science, Instem
Session Date and Time: Monday, November 18, 5:00-6.30 PM (CST)
Abstract Title: Collection of Evidence for Establishing Compound-Specific Limits for Extractables and Leachables
Presenting Author: Arianna Bassan, Principal Consultant, Innovatune. Co Author – Kevin Cross, Instem, PhD, VP Regulatory Science, Instem
Session Date and Time: Monday, November 18, 5:00-6.30 PM (CST)
